Health

Allergy caused by Peanuts are increasing

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Allergies are always there and children are more prone to the allergies. Peanuts and other food items causing allergies are on the peak and some experts are saying that there is some progress in controlling or preventing life-threatening reactions.

What is Food Allergy?

A food allergy is termed as allergy caused by the food. The immune system responds to foreign antigens in different ways and when the immune system responds abnormally to the food then it is food allergy.

Symptoms may include the itchiness, swelling of the particular area, diarrhea, vomiting, breathing problems, low blood pressure. It can take some minutes and also takes hours to show the symptoms. Several food items like cow’s milk, peanuts, fish, tree initiates allergic reactions in the body of many people. But risk of allergies may depend on person to person and family history. Allergies which occur may depend how the body reacts to some food particles. When immunoglobin E binds to the food particle. Then the inflammatory chemicals are released mainly histamine.

SYMPTOMS OF ALLERGY

  1. Rashes
  2. Swelling
  3. Fainting
  4. Runny nose
  5. Fainting
  6. Vomiting
  7. Nausea
  8. Diarrhea

Various drugmakers are working for the development of medicine to treat food allergy as body starts to attack the proteins which enters in the body. There is one method of treatment which will involve the process of introducing some small of amount of peanut into the one which will increase the tolerance level. A study from Jaffe Food Allergy institute at New York’s Mount Sinai Hospital told that the number of people suffering from the peanut allergies have been tripled from the year 1997 to 2008.

“It really is almost an epidemic,” Dr. Scott Sicherer, the institute’s director, told CNBC’s “On the Money.” “It’s impossible to deny an increase, even with anecdotal reports from school nurses,” he said, adding that “about two (children) per classroom have food allergies. It’s not just our imagination.”

National Institue of Health said early exposure could help prevent peanut allergies, with new clinical guidelines suggesting parents introduce peanut-containing foods to infants as “early as 4 to 6 months.” Sicherer said that peanut tolerance will affect the food allergy sufferers.”If you can increase the threshold let’s say from 1/100th of a peanut to two peanuts, that’s an amazing safety.”

It’s not just peanuts, though, with Sicherer citing milk, eggs, wheat, soy, fish and other nuts as being among the most common allergies. “They account for most of the food allergies, but you can be allergic to almost any food,” he said.

Many kids suffer from allergies from milk and egg and with time they fight against that with time but it is more harder to fight against the allergy of peanuts.

Sicherer, who is author of “Food Allergies: A Complete Guide for Eating When Your Life Depends on It,” said that one possible cause is “the cleanliness theory,” which suggests kids aren’t being exposed to the germs that help build up immunity.

“The thought is we just have such clean living now” that kids are on computers and not in playgrounds, he said.

As a result, “our immune system may be getting misdirected and attacking things that it doesn’t need to, because our immune system is the part of the body that’s supposed to protect us from germs,” he added. “But for allergies, it attacks the foods and makes us sick.”

Sicherer said treatments are “very promising, not just for peanuts but for other foods as well. The other amazing thing is that we have more than a dozen different therapies that are in the pipeline, that are actually being tried in people now to look at more foods.”

The ultimate goal is a full-fledged cure, the doctor said. “But in the meantime, safety is really a big part of it. When you’re living with a food allergy, it’s like you’re living in a landmine situation,” he added. “Every meal, every snack, every party, every social activity — is that food that can hurt me going to be there?”

When the symptoms becomes crucial it leads to a condition called as anaphylaxis. Anaphylaxis is a situation in which the person becomes unable to breathe and it can also take the life of an individual. The most widely used medicine is EpiPens, used to control the general allergies but till now no specific treatment have come up to cure peanut allergies. New therapies are discovered to cure peanut allergies.

AR101 from Aimmune Therapeutics, Viaskin Peanut from DBV Technologies, and ANB020 from AnaptysBio.

AR101 is one such pill which is having peanut flour. It is mixed in the food of the allergic person is less quantity, then after some time it is mixed in bit large quantity so that the allergic person will become more tolerant towards the peanut. Viaskin Peanut is another therapy which is used to treat peanut allergy. Basically Viaskin is a vaccination which is having skin patch of peanut which again increase the tolerance of allergic patient towards peanut proteins. This therapy was a successful programme. Children which were administered with the pills eventually have higher tolerance towards peanut allergy.

“Though exciting advances, people should understand that these therapies are not necessarily a ‘cure’ – patients won’t be able to trash their EpiPens or stop avoiding peanut products. To maintain the protection, the patient has to take the drugs indefinitely,” comments Rose Joachim, Immunology Analyst at GlobalData.

ANB020 is other therapy and it is not specific to the peanut only. This drug works in the different manner by inhibiting the immune system to start any further immune response.

Jenna Collier, an Immunology Ph.D. student at Harvard University, added that “these clinical trials are just the beginning – in the near future, we will likely see improvements on both safety and efficacy of treatments like these as we learn more about the complex mechanisms of peanut allergy and tolerance.”

“Though exciting advances, people should understand that these therapies are not necessarily a ‘cure’ – patients won’t be able to trash their EpiPens or stop avoiding peanut products. To maintain the protection, the patient has to take the drugs indefinitely,” comments Rose Joachim, Immunology Analyst at GlobalData.

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